Transcranial Brain Stimulation (TMS & TCS) are increasingly used in basic research to study brain-behavior-relationships and in clinical practice for treating various mental disorders such as depression. We now know that the effects of TMS/TCS are state-dependent causing large intra- and inter-subject variability and hindering its reproducibility on single-subject-level. We propose to overcome this fundamental limitation by using the pioneering approach of concurrent TMS+EEG+fMRI, enabling us to apply TMS/TCS at predefined oscillatory state moments (phases) or amplitudes (power) and probe state-dependent gating of brain stimulation within brain-wide functional networks. Once personalized and adapted, however, we need to also make the brain stimulation treatment more accessible and scalable, and thus start offering digital cloud-based home-administered solutions.

Our presenter is Prof. Dr. Alexander T. Sack, one of the world’s most renowned expert in noninvasive brain stimulation, fundamental and applied cognitive neuroscience, and clinical brain stimulation research. He is currently appointed as Chair and Full professor of Brain Stimulation and Applied Cognitive Neuroscience at the Faculty of Psychology & Neuroscience, Maastricht University, co-director of the interfaculty Center for Integrative Neuroscience (CIN), and scientific director of the TMS Clinic at the Maastricht University Medical Center (MUMC+). He is also Principal Investigator (PI) of the research section “Brain Stimulation and Cognition” at the Maastricht Brain Imaging Centre.

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